Method Development and Validation of Cefixime by Using RP-HPLC in Pharmaceutical Formulations

Analytical method development and validation are ongoing interconnected activities that essential in research development, quality control, assurance departments. They involve the creation testing of analytical procedures to assess equivalence manage risks effectively. These crucial for establishing specific acceptance criteria products ensuring reliability consistency results. Validations assessing whether an procedure is appropriate reliable its intended purpose. Literature survey reveals methods based on UV spectrometry, RP-HPLC HPTLC determination Cefixime individually combination with others drugs . The were validated according ICH guidelines terms accuracy, precision, lod, other aspects validation. developed cefixime have been designed be straightforward, making them easy perform. also demonstrated high sensitivity, enabling detection quantification at low concentrations. This sensitivity accurately determining amount present bulk samples or tablet formulations.